Hyalic Acid Eye Drop 0.18 is a type of eye drop solution that contains hyaluronic acid, a naturally occurring substance found in the body. Hyaluronic acid is a key component of the eye's vitreous humor and plays a crucial role in maintaining the eye's moisture and lubrication. The 0.18% concentration of hyaluronic acid in these eye drops is specifically designed to provide optimal moisturizing and soothing effects for dry, irritated eyes.
Composition and Mechanism of Action
The Hyalic Acid Eye Drop 0.18 solution is composed of 0.18% hyaluronic acid, which is a high molecular weight polysaccharide. This substance is capable of retaining large amounts of water, making it an effective humectant that helps to lock in moisture and soothe dry eyes. When applied to the eye, the hyaluronic acid in the eye drops forms a thin, protective film on the surface of the eye, reducing friction and discomfort caused by dryness. The high viscosity of the solution also helps to prolong the residence time of the eye drops on the eye surface, allowing for a more sustained release of hyaluronic acid.
Indications and Uses
The Hyalic Acid Eye Drop 0.18 is indicated for the treatment of dry eye syndrome, a common condition characterized by insufficient tear production or poor tear quality. This condition can be caused by a variety of factors, including blepharitis, conjunctivitis, and environmental factors such as wind, dust, or dry air. The eye drops are also suitable for use in patients who wear contact lenses, as they can help to reduce discomfort and irritation associated with lens wear. Additionally, the hyaluronic acid in the eye drops can help to promote wound healing and reduce inflammation in the eye.
| Ingredient | Concentration |
|---|---|
| Hyaluronic Acid | 0.18% |
| Purified Water | QS |
| Preservatives | Yes |
Clinical Efficacy and Safety
The efficacy and safety of the Hyalic Acid Eye Drop 0.18 have been evaluated in several clinical studies. In a randomized, double-blind, placebo-controlled trial, patients with dry eye syndrome who were treated with the Hyalic Acid Eye Drop 0.18 showed significant improvements in tear film stability and ocular surface health compared to those who received a placebo. Additionally, the eye drops were well-tolerated, with minimal adverse effects reported. Corneal staining and conjunctival hyperemia were the most common adverse effects observed, but these were generally mild and transient.
Pharmacokinetics and Pharmacodynamics
The pharmacokinetics of hyaluronic acid in the eye have not been extensively studied. However, it is known that hyaluronic acid is rapidly absorbed into the corneal stroma and conjunctival tissue after topical application. The pharmacodynamic effects of the Hyalic Acid Eye Drop 0.18 are thought to be mediated by the hydration of the ocular surface and the reduction of friction between the cornea and the eyelids. The eye drops may also have anti-inflammatory effects, which can help to reduce the severity of dry eye symptoms.
- The Hyalic Acid Eye Drop 0.18 is available in a 10ml bottle
- The recommended dosage is 1-2 drops per eye, 2-3 times daily
- The eye drops should be used for a minimum of 2 weeks to achieve optimal effects
- Patients should consult their doctor or pharmacist before using the eye drops, especially if they have a history of eye surgery or other eye conditions
Can the Hyalic Acid Eye Drop 0.18 be used in patients with sensitive eyes?
+Yes, the Hyalic Acid Eye Drop 0.18 is suitable for use in patients with sensitive eyes. However, it is recommended to start with a low frequency of application (e.g., once daily) and gradually increase as needed and tolerated.
Can the Hyalic Acid Eye Drop 0.18 be used in combination with other eye drops?
+Yes, the Hyalic Acid Eye Drop 0.18 can be used in combination with other eye drops, but it is recommended to consult a doctor or pharmacist before doing so. The eye drops should be administered at least 5 minutes apart to avoid any potential interactions.
